Advantages of glove box vacuum chambers include the capability of generating and maintaining an inert atmosphere — a necessity for moisture- and oxygen-sensitive reactions. They provide a high degree of safety by containing hazardous materials from the environment and personnel. A vacuum system allows better control of the internal environment to remove traces of contaminants. Additionally, the chambers can be tailored to particular experimental requirements and are frequently equipped with vacuum gauges and gas purification systems to finely tune the internal atmosphere. How Materials and Equipment Are Passed In and Out of the Vacuum Chamber Design also builds provision into the vacuum chamber to transfer materials and equipment in and out of the isolated environment without breaching the controlled conditions.